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Medientyp: E-Artikel Titel: Sinonasal adenocarcinoma: A rare second malignancy in long term retinoblastoma survivors Beteiligte: Bhagia, Pooja; Colanta, Agnes Basas; Abramson, David H.; Carlson, Diane L.; Kleinerman, Ruth A.; Kraus, Dennis; Dunkel, Ira J. Erschienen: Wiley, 2011 Erschienen in: Pediatric Blood & Cancer, 57 (2011) 4, Seite 693-695 Sprache: Englisch DOI: 10.1002/pbc.23161 ISSN: 1545-5009; 1545-5017 Entstehung: Anmerkungen: Beschreibung: AbstractRetinoblastoma is the most common primary cancer of the eye in children. The incidence of second tumors in survivors of bilateral retinoblastoma and in survivors of unilateral retinoblastoma who presumably carry a germline RB1 mutation is documented. This article describes the previously unrecognized association of sinonasal adenocarcinoma as a second malignancy in retinoblastoma survivors. We present three cases who received radiation therapy as a part of their treatment and developed sinonasal adenocarcinoma as a second malignancy. Sinonasal adenocarcinoma should be considered as a second malignancy in retinoblastoma survivors who present with vague sinus symptoms. Pediatr Blood Cancer 2011; 57: 693–695. © 2011 Wiley‐Liss, Inc.