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Lee, Chi‐Hoon; Kim, Hyung‐Wook; Lee, Hoi‐Seon

Acaricidal properties of piperazine and its derivatives against house‐dust and stored‐food mites

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  • Medientyp: E-Artikel
  • Titel: Acaricidal properties of piperazine and its derivatives against house‐dust and stored‐food mites
  • Beteiligte: Lee, Chi‐Hoon; Kim, Hyung‐Wook; Lee, Hoi‐Seon
  • Erschienen: Wiley, 2009
  • Erschienen in: Pest Management Science
  • Sprache: Englisch
  • DOI: 10.1002/ps.1728
  • ISSN: 1526-4998; 1526-498X
  • Schlagwörter: Insect Science ; Agronomy and Crop Science ; General Medicine
  • Entstehung:
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  • Beschreibung: <jats:title>Abstract</jats:title><jats:p><jats:bold>BACKGROUND:</jats:bold> Piperazine derivatives possess pharmacological properties, yet the acaricidal activity of these compounds has not been investigated. This study was conducted to evaluate the colour alteration and acaricidal activity of piperazine derivatives against <jats:italic>Dermatophagoides</jats:italic> spp. and <jats:italic>Tyrophagus putrescentiae</jats:italic> (Schrank) using filter paper and fumigant methods.</jats:p><jats:p><jats:bold>RESULTS:</jats:bold> In a fumigant bioassay, 1‐phenylpiperazine (7.83 µg cm<jats:sup>−2</jats:sup>) against <jats:italic>D. farinae</jats:italic> (Hughes) was found to be 4.7 times more toxic than DEET (36.84 µg cm<jats:sup>−2</jats:sup>), followed by benzyl benzoate (9.72 µg cm<jats:sup>−2</jats:sup>), piperazine (11.41 µg cm<jats:sup>−2</jats:sup>), 1‐ethoxycarbonylpiperazine (20.14 µg cm<jats:sup>−2</jats:sup>) and 1‐(2‐methoxyphenyl)piperazine (22.14 µg cm<jats:sup>−2</jats:sup>). In a filter paper bioassay, 1‐(2‐methoxyphenyl)piperazine (3.65 µg cm<jats:sup>−2</jats:sup>) was 5.7 times more toxic than DEET (20.64 µg cm<jats:sup>−2</jats:sup>), followed by 1‐ethoxycarbonylpiperazine (4.02 µg cm<jats:sup>−2</jats:sup>), 1‐phenylpiperazine (4.75 µg cm<jats:sup>−2</jats:sup>), benzyl benzoate (7.83 µg cm<jats:sup>−2</jats:sup>) and piperazine (10.59 µg cm<jats:sup>−2</jats:sup>). Similar results have been exhibited with piperazine derivatives against <jats:italic>D. pteronyssinus</jats:italic> (Troussart). However, no activity against <jats:italic>T. putrescentiae</jats:italic> was observed for piperazine derivatives, except for piperazine.</jats:p><jats:p><jats:bold>CONCLUSIONS:</jats:bold> These results indicate that piperazine derivatives may be suitable as vapour‐phase acaricide fumigants owing to their high volatility, acaricidal activity and safety. 1‐Phenylpiperazine was found to be an excellent mite indicator based on the colour change it induced. Taken together, these findings indicate that piperazine derivatives may be used to replace existing problematical acaricides owing to their activity and ability to act as a mite indicator. Copyright © 2009 Society of Chemical Industry</jats:p>