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James, Steven; Perry, Lin; Lowe, Julia; Harris, Margaret; Colman, Peter G.; Craig, Maria E.; Anderson, Kym; Andrikopoulos, Sof; Ambler, Geoff; Barrett, Helen; Batch, Jenny; Bergman, Philip; Cameron, Fergus; Conwell, Louise; Cotterill, Andrew; Cooper, Chris; Couper, Jennifer; Davis, Elizabeth; de Bock, Martin; Donaghue, Kim; Fairchild, Jan; Fegan, Gerry; Fourlanos, Spiros; Glastras, Sarah; [...]

Blood pressure in adolescents and young adults with type 1 diabetes: data from the Australasian Diabetes Data Network registry

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  • Medientyp: E-Artikel
  • Titel: Blood pressure in adolescents and young adults with type 1 diabetes: data from the Australasian Diabetes Data Network registry
  • Beteiligte: James, Steven; Perry, Lin; Lowe, Julia; Harris, Margaret; Colman, Peter G.; Craig, Maria E.; Anderson, Kym; Andrikopoulos, Sof; Ambler, Geoff; Barrett, Helen; Batch, Jenny; Bergman, Philip; Cameron, Fergus; Conwell, Louise; Cotterill, Andrew; Cooper, Chris; Couper, Jennifer; Davis, Elizabeth; de Bock, Martin; Donaghue, Kim; Fairchild, Jan; Fegan, Gerry; Fourlanos, Spiros; Glastras, Sarah; [...]
  • Erschienen: Springer Science and Business Media LLC, 2023
  • Erschienen in: Acta Diabetologica
  • Sprache: Englisch
  • DOI: 10.1007/s00592-023-02057-4
  • ISSN: 1432-5233
  • Schlagwörter: Endocrinology ; General Medicine ; Endocrinology, Diabetes and Metabolism ; Internal Medicine
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:title>Abstract</jats:title><jats:sec> <jats:title>Aim</jats:title> <jats:p>Hypertension increases complication risk in type 1 diabetes (T1D). We examined blood pressure (BP) in adolescents and young adults with T1D from the Australasian Diabetes Data Network, a prospective clinical diabetes registry in Australia and New Zealand.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>This was a longitudinal study of prospectively collected registry data. Inclusion criteria: T1D (duration ≥ 1 year) and age 16–25 years at last visit (2011–2020). Hypertension was defined as (on ≥ 3 occasions) systolic BP and/or diastolic BP &gt; 95<jats:sup>th</jats:sup> percentile for age &lt; 18 years, and systolic BP &gt; 130 and/or diastolic BP &gt; 80 mmHg for age ≥ 18 years. Multivariable Generalised Estimating Equations were used to examine demographic and clinical factors associated with BP in the hypertensive range across all visits.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>Data from 6338 young people (male 52.6%) attending 24 participating centres across 36,655 T1D healthcare visits were included; 2812 (44.4%) had BP recorded at last visit. Across all visits, 19.4% of youth aged &lt; 18 years and 21.7% of those aged ≥ 18 years met criteria for hypertension. In both age groups, BP in the hypertensive range was associated with male sex, injection (vs. pump) therapy, higher HbA1c, and higher body mass index.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusions</jats:title> <jats:p>There is a high proportion of adolescents and young adults reported with BP persistently in hypertensive ranges. Findings flag the additive contribution of hypertension to the well-established body of evidence indicating a need to review healthcare models for adolescents and young adults with T1D.</jats:p> </jats:sec>