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Santacroce, Giovanni; Lenti, Marco Vincenzo; Abruzzese, Giulia Maria; Alunno, Giacomo; Di Terlizzi, Francesco; Frenna, Carmine; Gentile, Antonella; Latorre, Mario Andrea; Petrucci, Clarissa; Ruggeri, Damiano; Soriano, Simone; Aronico, Nicola; Rossi, Carlo Maria; De Silvestri, Annalisa; Corazza, Gino Roberto; Di Sabatino, Antonio

Diagnostic delay in symptomatic uncomplicated diverticular disease: an Italian tertiary referral centre study

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  • Medientyp: E-Artikel
  • Titel: Diagnostic delay in symptomatic uncomplicated diverticular disease: an Italian tertiary referral centre study
  • Beteiligte: Santacroce, Giovanni; Lenti, Marco Vincenzo; Abruzzese, Giulia Maria; Alunno, Giacomo; Di Terlizzi, Francesco; Frenna, Carmine; Gentile, Antonella; Latorre, Mario Andrea; Petrucci, Clarissa; Ruggeri, Damiano; Soriano, Simone; Aronico, Nicola; Rossi, Carlo Maria; De Silvestri, Annalisa; Corazza, Gino Roberto; Di Sabatino, Antonio
  • Erschienen: Springer Science and Business Media LLC, 2024
  • Erschienen in: Internal and Emergency Medicine
  • Sprache: Englisch
  • DOI: 10.1007/s11739-023-03446-x
  • ISSN: 1828-0447; 1970-9366
  • Schlagwörter: Emergency Medicine ; Internal Medicine
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:title>Abstract</jats:title><jats:p>The magnitude of the diagnostic delay of symptomatic uncomplicated diverticular disease (SUDD) is unknown; we aimed to evaluate SUDD diagnostic delay and its risk factors. SUDD patients diagnosed at a tertiary referral centre were retrospectively enrolled (2010–2022). Demographic and clinical data were retrieved. Overall, patient-, and physician-dependant diagnostic delays were assessed. Univariate and multivariate analyses were fitted to identify risk factors for diagnostic delay. Overall, 70 SUDD patients (median age 65 years, IQR 52–74; F:M ratio = 1.6:1) were assessed. The median overall diagnostic delay was 7 months (IQR 2–24), patient-dependant delay was 3 months (IQR 0–15), and physician-dependant delay was 1 month (IQR 0–6). Further, 25% of patients were misdiagnosed with irritable bowel syndrome (IBS). At multivariate analysis, previous misdiagnosis was a significant risk factor for overall and physician-dependant diagnostic delay (OR 9.99, p = 0.01, and OR 6.46, p = 0.02, respectively). Also, a high educational level (&gt; 13 years) was associated with a greater overall diagnostic delay (OR 8.74 p = 0.02), while previous abdominal surgery was significantly associated to reduced physician-dependant diagnostic delay (OR 0.19 p = 0.04). To conclude, SUDD may be diagnosed late, IBS being the most frequent misdiagnosis. Timely diagnosis is crucial to tackle the burden of SUDD on patients and healthcare.</jats:p>