Beschreibung:
<jats:title>Abstract</jats:title><jats:p>Detection and quantification of tumor-derived mutations in cell-free DNA (cfDNA) holds great potential for non-invasive tumor diagnostics and molecular monitoring. We developed highly sensitive discriminatory multi-target digital droplet PCR (ddPCR) assays covering 14 <jats:italic>KRAS</jats:italic> and <jats:italic>NRAS</jats:italic> hotspot mutations.</jats:p>