Beschreibung:
<jats:title>Abstract</jats:title><jats:p>Metallo-<jats:italic>β</jats:italic>-lactamases (MBL) are a threat to public health, since they dramatically limit the use of <jats:italic>β</jats:italic>-lactams. We report the isolation of a multidrug-resistant <jats:italic>Hafnia paralvei</jats:italic> strain from urine and a rectal swab of a female patient after allogeneic hematopoietic stem cell transplantation for myelodysplastic syndrome. Antimicrobial susceptibility testing yielded resistance to trimethoprim/sulfamethoxazole, colistin, fosfomycin and all <jats:italic>β</jats:italic>-lactams, except cefiderocol. Whole genome sequencing revealed the presence of plasmid-encoded NDM-1 and VIM-1 carbapenemases. This finding highlights the importance of epidemiological surveillance and new therapeutic options for MBL.</jats:p>