Beschreibung:
<jats:title>Abstract</jats:title><jats:sec id="S1355617721000084_as1"><jats:title>Objective:</jats:title><jats:p>The relevance of the episodic memory in the prediction of brain aging is well known. The Face Name Associative Memory Exam (FNAME) is a valued associative memory measure related to Alzheimer’s disease (AD) biomarkers, such as amyloid-β deposition preclinical AD individuals. Previous validation of the Spanish version of the FNAME test (S-FNAME) provided normative data and psychometric characteristics. The study was limited to subjects attending a memory clinic and included a reduced sample with gender inequality distribution. The purpose of this study was to assess S-FNAME psychometric properties and provide normative data in a larger independent sample of cognitively healthy individuals.</jats:p></jats:sec><jats:sec id="S1355617721000084_as2"><jats:title>Method:</jats:title><jats:p>S-FNAME was administered to 511 cognitively healthy volunteers (242 women, aged 41–65 years) participating in the Barcelona Brain Health Initiative cohort study.</jats:p></jats:sec><jats:sec id="S1355617721000084_as3"><jats:title>Results:</jats:title><jats:p>Factor analysis supported construct validity revealing two underlying components: face-name and face-occupation and explaining 95.34% of the total variance, with satisfactory goodness of fit. Correlations between S-FNAME and Rey Auditory-Verbal Learning Test were statistically significant and confirmed its convergent validity. We also found weak correlations with non-memory tests supporting divergent validity. Women showed better scores, and S-FNAME was positively correlated with education and negatively with age. Finally, we generated normative data.</jats:p></jats:sec><jats:sec id="S1355617721000084_as4"><jats:title>Conclusions:</jats:title><jats:p>The S-FNAME test exhibits good psychometric properties, consistent with previous findings, resulting in a valid and reliable tool to assess episodic memory in cognitively healthy middle-aged adults. It is a promising test for the early detection of subtle memory dysfunction associated with abnormal brain aging.</jats:p></jats:sec>