Beschreibung:
<jats:title>Abstract</jats:title><jats:sec id="S1355617722000698_as1"><jats:title>Objectives:</jats:title><jats:p>People living with HIV (PLWH) often experience deficits in the strategic/executive aspects of prospective memory (PM) that can interfere with instrumental activities of daily living. This study used a conceptual replication design to determine whether cognitive intraindividual variability, as measured by dispersion (IIV-dispersion), contributes to PM performance and symptoms among PLWH.</jats:p></jats:sec><jats:sec id="S1355617722000698_as2"><jats:title>Methods:</jats:title><jats:p>Study 1 included 367 PLWH who completed a comprehensive clinical neuropsychological test battery, the Memory for Intentions Test (MIsT), and the Prospective and Retrospective Memory Questionnaire (PRMQ). Study 2 included 79 older PLWH who completed the Cogstate cognitive battery, the Cambridge Prospective Memory Test (CAMPROMPT), an experimental measure of time-based PM, and the PRMQ. In both studies, a mean-adjusted coefficient of variation was derived to measure IIV-dispersion using normative <jats:italic>T</jats:italic>-scores from the cognitive battery.</jats:p></jats:sec><jats:sec id="S1355617722000698_as3"><jats:title>Results:</jats:title><jats:p>Higher IIV-dispersion was significantly associated with lower time-based PM performance at small-to-medium effect sizes in both studies (mean <jats:italic>r</jats:italic><jats:sub><jats:italic>s</jats:italic></jats:sub> = −0.30). The relationship between IIV-dispersion and event-based PM performance was comparably small in magnitude in both studies (<jats:italic>r</jats:italic><jats:sub><jats:italic>s</jats:italic></jats:sub> = −0.19, −0.20), but it was only statistically significant in Study 1. IIV-dispersion showed very small, nonsignificant relationships with self-reported PM symptoms in both samples (<jats:italic>r</jats:italic><jats:sub><jats:italic>s</jats:italic></jats:sub> < 0.10).</jats:p></jats:sec><jats:sec id="S1355617722000698_as4"><jats:title>Conclusions:</jats:title><jats:p>Extending prior work in healthy adults, these findings suggest that variability in performance across a cognitive battery contributes to laboratory-based PM accuracy, but not perceived PM symptoms, among PLWH. Future studies might examine whether daily fluctuations in cognition or other aspects of IIV (e.g., inconsistency) play a role in PM failures in everyday life.</jats:p></jats:sec>