Beschreibung:
<jats:title>Abstract</jats:title><jats:sec id="S1368980017004013_abs1" sec-type="general"><jats:title>Objective</jats:title><jats:p>Low and high birth weight have been associated with increased risk of type 2 diabetes and CVD. Diet could partly mediate this association, e.g. by intra-uterine programming of unhealthy food preferences. We examined the association of birth weight with diet in Finnish children.</jats:p></jats:sec><jats:sec id="S1368980017004013_abs2" sec-type="general"><jats:title>Design</jats:title><jats:p>Birth weight standard deviation score (SDS) was calculated using national birth register data and Finnish references. Dietary factors were assessed using 4 d food records. Diet quality was defined by the Finnish Children Healthy Eating Index (FCHEI).</jats:p></jats:sec><jats:sec id="S1368980017004013_abs3" sec-type="general"><jats:title>Setting</jats:title><jats:p>The Physical Activity and Nutrition in Children (PANIC) study.</jats:p></jats:sec><jats:sec id="S1368980017004013_abs4" sec-type="subjects"><jats:title>Subjects</jats:title><jats:p>Singleton, full-term children (179 girls, 188 boys) aged 6–8 years.</jats:p></jats:sec><jats:sec id="S1368980017004013_abs5" sec-type="results"><jats:title>Results</jats:title><jats:p>Birth weight was inversely associated (standardized regression coefficient<jats:italic>β</jats:italic>; 95 % CI) with FCHEI (−0·15; −0·28, −0·03) in all children and in boys (−0·27; −0·45, −0·09) but not in girls (−0·01; −0·21, 0·18) after adjusting for potential confounders (<jats:italic>P</jats:italic>=0·044 for interaction). Moreover, higher birth weight was associated with lower fruit and berries consumption (−0·13; −0·25, 0·00), higher energy intake (0·17; 0·05, 0·29), higher sucrose intake (0·19; 0·06, 0·32) and lower fibre intake (−0·14; −0·26, −0·01). These associations were statistically non-significant after correction for multiple testing. Children with birth weight >1 SDS had higher sucrose intake (mean; 95 % CI) as a percentage of energy intake (14·3 E%; 12·6, 16·0 E%) than children with birth weight of −1 to 1 SDS (12·8 E%; 11·6, 14·0 E%) or <−1 SDS (12·4 E%; 10·8, 13·9 E%;<jats:italic>P</jats:italic>=0·036).</jats:p></jats:sec><jats:sec id="S1368980017004013_abs6" sec-type="conclusions"><jats:title>Conclusions</jats:title><jats:p>Higher birth weight may be associated with unhealthy diet in childhood.</jats:p></jats:sec>