• Medientyp: E-Artikel
  • Titel: Curation of NISEED, an integrative framework for the digital representation of embryonic development
  • Beteiligte: Dauga, Delphine; Tassy, Olivier; Daian, Fabrice; Sobral, Daniel; Lemaire, Patrick
  • Erschienen: Springer Science and Business Media LLC, 2009
  • Erschienen in: Nature Precedings
  • Sprache: Englisch
  • DOI: 10.1038/npre.2009.3168.1
  • ISSN: 1756-0357
  • Schlagwörter: Marketing ; Organizational Behavior and Human Resource Management ; Strategy and Management ; Drug Discovery ; Pharmaceutical Science ; Pharmacology
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  • Beschreibung: <jats:title>Abstract</jats:title><jats:p>NISEED (Network for In situ Expression and Embryological Data) is a generic infrastructure for the creation, maintenance and integration of molecular and anatomical information on model organisms. We applied it to ascidians which are marine invertebrate chordates. These animals constitute model organisms of choice for developmental biology because their embryos develop with a small number of cells and an invariant lineage, allowing their study with a cellular level of resolution. In ANISEED (Ascidian NISEED), embryogenesis of ascidian is represented at the level of the genome via functional gene annotations, cis-regulatory elements or gene expression data, at the level of the cell by representing its morphology, fates, lineage, and relations with its neighbors, or at the level of the whole embryo by representing its anatomy and morphogenesis at successive developmental stages. The system provides also tool and standard to enter, annotate, curate and manage data. All results can be accessed through the ANISEED website at "http://aniseed-ibdm.univ-mrs.fr":http://aniseed-ibdm.univ-mrs.fr</jats:p>
  • Zugangsstatus: Freier Zugang