• Medientyp: E-Artikel
  • Titel: Defined pH-sensitive nanogels as gene delivery platform for siRNA mediated in vitro gene silencing
  • Beteiligte: Dimde, Mathias; Neumann, Falko; Reisbeck, Felix; Ehrmann, Svenja; Cuellar-Camacho, Jose Luis; Steinhilber, Dirk; Ma, Nan; Haag, Rainer
  • Erschienen: Royal Society of Chemistry (RSC), 2017
  • Erschienen in: Biomater. Sci.
  • Sprache: Englisch
  • DOI: 10.1039/c7bm00729a
  • ISSN: 2047-4830; 2047-4849
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  • Beschreibung: <p>An advanced cationic carrier system which combines high transfection efficiency with low cytotoxicity and a control over the release of the encapsulated genetic material by the reduction of the multivalent architecture upon pH triggered degradation was developed.</p>