Bromo- and glycosyl-substituted BODIPYs for application in photodynamic therapy and imaging

Medientyp: E-Artikel
Titel: Bromo- and glycosyl-substituted BODIPYs for application in photodynamic therapy and imaging
Beteiligte: Hohlfeld, Benjamin F.; Steen, Dorika; Wieland, Gerhard D.; Achazi, Katharina; Kulak, Nora; Haag, Rainer; Wiehe, Arno
Erschienen: Royal Society of Chemistry (RSC), 2023
Erschienen in: Organic & Biomolecular Chemistry, 21 (2023) 15, Seite 3105-3120
Sprache: Englisch
DOI: 10.1039/d2ob02174a
ISSN: 1477-0520; 1477-0539
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Beschreibung: <jats:p>Structurally diverse BODIPYs were evaluated for their phototoxic activity against four cancer cell lines in a PDT optimization approach. In particular, glycosylated dibromo-BODIPYs showed a high phototoxic effect, as well as pronounced cellular uptake.</jats:p>

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