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Medientyp:
E-Artikel
Titel:
Lhermitte's Sign Developing after IMRT for Head and Neck Cancer
Beteiligte:
Lim, Dong C.;
Gagnon, Patrick J.;
Meranvil, Sophia;
Kaurin, Darryl;
Lipp, Linda;
Holland, John M.
Erschienen:
Hindawi Limited, 2010
Erschienen in:International Journal of Otolaryngology
Sprache:
Englisch
DOI:
10.1155/2010/907960
ISSN:
1687-921X;
1687-9201
Entstehung:
Anmerkungen:
Beschreibung:
<jats:p><jats:italic>Background</jats:italic>. Lhermitte's sign (LS) is a benign form of myelopathy with neck flexion producing an unpleasant electric-shock sensation radiating down the extremities. Although rare, it can occur after head and neck radiotherapy.<jats:italic>Results</jats:italic>. We report a case of Lhermitte's developing after curative intensity-modulated radiotherapy (IMRT) for a patient with locoregionally advanced oropharyngeal cancer. IMRT delivers a conformal dose of radiation in head and neck cancer resulting in a gradient of radiation dose throughout the spinal cord. Using IMRT, more dose is delivered to the anterior spinal cord than the posterior cord.<jats:italic>Conclusions</jats:italic>. Lhermitte's sign can develop after IMRT for head and neck cancer. We propose an anterior spinal cord structure, the spinothalamic tract to be the target of IMRT-caused LS.</jats:p>