Beschreibung:
<jats:p>Cu(II) complexes of 1-[4-(3-ethyl-piperidine-2,6-dione)-3-yl]-phenyl-2,4,6-trisubstituted
pyridinium perchlorates, containing alkyl, aryl and combinations of these two types of moieties in their
molecule were synthesized and characterized by elemental analysis, spectroscopy, magnetic,
thermogravimetric and conductimetric measurements. In these complexes, Cu(II) ions are in octahedral
geometry with four water molecules occupying the equatorial coordination sites and the two organic ligands
in deprotonated state the remaining axial ones. The donor atom of these ligands is constituted by the ionized
nitrogen of the glutarimide moiety. The new derivatives possess weak inhibitory activity towards the zinc
enzyme carbonic anhydrase.</jats:p>