• Medientyp: E-Artikel
  • Titel: Male Circumcision and Serologically Determined Human Papillomavirus Infection in a Birth Cohort
  • Beteiligte: Dickson, Nigel P.; Ryding, Janka; van Roode, Thea; Paul, Charlotte; Herbison, Peter; Dillner, Joakim; Skegg, David C.G.
  • Erschienen: American Association for Cancer Research (AACR), 2009
  • Erschienen in: Cancer Epidemiology, Biomarkers & Prevention
  • Sprache: Englisch
  • DOI: 10.1158/1055-9965.epi-08-0353
  • ISSN: 1055-9965; 1538-7755
  • Schlagwörter: Oncology ; Epidemiology
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:title>Abstract</jats:title><jats:p>Circumcision has been reported to protect against infection with human papillomavirus (HPV) in men, but results have been inconsistent. We followed males in a birth cohort born in Dunedin, New Zealand, in 1972 and 1973 from age 3 to 32 years. Seropositivity at age 32 years for the oncogenic types HPV-16 and 18, and the nononcogenic types 6 and 11, was studied in relation to maternal reports of circumcision status at age 3 for 450 men. Seropositivity to any of these types was associated with lifetime number of sexual partners (P = 0.03), and lower moral-religious emphasis of the family of origin (P &amp;lt; 0.001). Circumcision was not found to be protective, with the adjusted odds ratio (95% confidence interval) for HPV6/11/16/18 seropositivity among the circumcised compared with the uncircumcised being 1.4 (0.89-2.2). (Cancer Epidemiol Biomarkers Prev 2009;18(1):177–83)</jats:p>
  • Zugangsstatus: Freier Zugang