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Zepeda-Romero, Luz Consuelo; Lundgren, Pia; Gutierrez-Padilla, Jose Alfonso; Gomez-Ruiz, Larissa Maria; Quiles Corona, Moises; Orozco-Monroy, José Víctor; Barragan-Sánchez, Andrea; Razo-Cervantes, Juan Carlos; Löfqvist, Chatarina; Hård, Anna-Lena; Hellström, Ann

Oxygen Monitoring Reduces the Risk for Retinopathy of Prematurity in a Mexican Population

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  • Medientyp: E-Artikel
  • Titel: Oxygen Monitoring Reduces the Risk for Retinopathy of Prematurity in a Mexican Population
  • Beteiligte: Zepeda-Romero, Luz Consuelo; Lundgren, Pia; Gutierrez-Padilla, Jose Alfonso; Gomez-Ruiz, Larissa Maria; Quiles Corona, Moises; Orozco-Monroy, José Víctor; Barragan-Sánchez, Andrea; Razo-Cervantes, Juan Carlos; Löfqvist, Chatarina; Hård, Anna-Lena; Hellström, Ann
  • Erschienen: S. Karger AG, 2016
  • Erschienen in: Neonatology
  • Sprache: Englisch
  • DOI: 10.1159/000445040
  • ISSN: 1661-7800; 1661-7819
  • Schlagwörter: Developmental Biology ; Pediatrics, Perinatology and Child Health
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;/i&gt;&lt;/b&gt; Retinopathy of prematurity (ROP), a potentially blinding disease, affects preterm infants. High levels of oxygen saturation are a well-known risk factor for ROP. &lt;b&gt;&lt;i&gt;Objectives:&lt;/i&gt;&lt;/b&gt; To assess the frequency of ROP type 1 needing treatment after improved oxygen monitoring (2011) in a Mexican preterm population selected for WINROP analyses and to retrospectively revalidate WINROP, an online surveillance system identifying infants at risk of developing ROP type 1. &lt;b&gt;&lt;i&gt;Methods:&lt;/i&gt;&lt;/b&gt; Preterm infants born with birth weight (BW) &lt;1,750 g and/or at gestational age (GA) ≤34 weeks, screened for ROP in 2012-2014 at the Hospital Civil de Guadalajara, Mexico were included (n = 151). Eighty-five infants with GA &lt;32 weeks qualified for WINROP analyses. GA, BW, maximal ROP stage, ROP treatment and weekly weights were recorded. The results in the present study were compared to those of a previous WINROP study in the same hospital (2005-2010; n = 352). &lt;b&gt;&lt;i&gt;Results:&lt;/i&gt;&lt;/b&gt; In the present WINROP cohort, 11.8% of the infants born at GA &lt;32 weeks received treatment compared to 51.0% of the infants in the previous WINROP cohort. One infant (3%) born at GA ≥32 weeks received treatment during the present study period compared to 35.6% during the previous period. WINROP displayed 80.0% sensitivity in infants born at GA &lt;32 weeks in the present study compared to 84.7% in the previous study. &lt;b&gt;&lt;i&gt;Conclusions:&lt;/i&gt;&lt;/b&gt; Uncontrolled oxygen supplementation is the major risk factor for severe ROP in infants born at GA ≥32 weeks. After improved oxygen monitoring, the frequency of ROP treatment was dramatically reduced at the Hospital Civil de Guadalajara, Mexico.</jats:p>