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Pavone, Carlo; Romeo, Salvatore; D'Amato, Francesco; Usala, Manuela; Letizia Mauro, Giulia; Caruana, Giovanni; Caruana, Giovanni

Does Transfer Capacitive Resistive Energy Has a Therapeutic Effect on Peyronie's Disease? Randomized, Single-Blind, Sham-Controlled Study on 96 Patients: Fast Pain Relief

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  • Medientyp: E-Artikel
  • Titel: Does Transfer Capacitive Resistive Energy Has a Therapeutic Effect on Peyronie's Disease? Randomized, Single-Blind, Sham-Controlled Study on 96 Patients: Fast Pain Relief
  • Beteiligte: Pavone, Carlo; Romeo, Salvatore; D'Amato, Francesco; Usala, Manuela; Letizia Mauro, Giulia; Caruana, Giovanni; Caruana, Giovanni
  • Erschienen: S. Karger AG, 2017
  • Erschienen in: Urologia Internationalis
  • Sprache: Englisch
  • DOI: 10.1159/000467396
  • ISSN: 0042-1138; 1423-0399
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:p>&lt;b&gt;&lt;i&gt;Background/Aims/Objectives:&lt;/i&gt;&lt;/b&gt; We have investigated the clinical and physiological effects of Transfer Capacitive Resistive Energy (TCARE) therapy on men with Peyronie's disease (PD). &lt;b&gt;&lt;i&gt;Methods:&lt;/i&gt;&lt;/b&gt; Ninety-six men with PD have been randomized in a 2:1 ratio to receive 3 sessions of TCARE therapy or sham therapy. Pain, penile curvature and erectile function have been assessed before the first treatment and up to 9 months after the end of treatment, using the Visual Analogue Scale for the pain, a goniometer to measure the degree of curvature using at-home photography and an International Index of Erectile Function (IIEF-5) questionnaire. &lt;b&gt;&lt;i&gt;Results:&lt;/i&gt;&lt;/b&gt; A significant pain reduction at the end of the treatment in 51 (79.6%) patients (&lt;i&gt;p&lt;/i&gt; &lt; 0.01) of the treated group was observed. No significant improvements in the sham group (&lt;i&gt;p&lt;/i&gt; = 0.23) have been observed. No statistical differences in the degree of curvature have been observed in both groups. No statistical improvements have been observed in the IIEF-5 questionnaire. Adverse events have not been reported. &lt;b&gt;&lt;i&gt;Conclusion:&lt;/i&gt;&lt;/b&gt; This is, to our knowledge, the first randomized, single-blind, sham-controlled study that shows that TCARE has a positive short-term clinical effect on pain in patients with PD. The feasibility and tolerability of this treatment produce an attractive new therapeutic option for men with PD.</jats:p>