Erschienen in:
Acta Haematologica, 110 (2003) 2-3, Seite 160-170
Sprache:
Englisch
DOI:
10.1159/000072466
ISSN:
0001-5792;
1421-9662
Entstehung:
Anmerkungen:
Beschreibung:
Evidence that immunological effector mechanisms contribute to the elimination of leukemic blasts in allogeneic bone marrow transplantation supports the concept that the immune system plays a prominent role in the control of leukemic disease. For patients with high-risk acute leukemia, relapse prevention in the setting of minimal residual disease is paramount. This review discusses vaccine strategies aimed to stimulate a leukemia-specific immune response in vivo.