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Vinding, Gabrielle R.; Esmann, Solveig; Olesen, Anne B.; Hansen, Lone B.; Christensen, Karl B.; Jemec, Gregor B.E.

Interpretation of the Skin Cancer Quality of Life Score: A Validated Quality of Life Questionnaire for Non-Melanoma Skin Cancer

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  • Medientyp: E-Artikel
  • Titel: Interpretation of the Skin Cancer Quality of Life Score: A Validated Quality of Life Questionnaire for Non-Melanoma Skin Cancer
  • Beteiligte: Vinding, Gabrielle R.; Esmann, Solveig; Olesen, Anne B.; Hansen, Lone B.; Christensen, Karl B.; Jemec, Gregor B.E.
  • Erschienen: S. Karger AG, 2014
  • Erschienen in: Dermatology
  • Sprache: Englisch
  • DOI: 10.1159/000362807
  • ISSN: 1018-8665; 1421-9832
  • Schlagwörter: Dermatology
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;/i&gt;&lt;/b&gt; Health-related quality of life (HRQoL) instruments are used increasingly. In order to assign clinical meaning to HRQoL scores, the interpretation of instruments is essential but lagging in dermatology. &lt;b&gt;&lt;i&gt;Objective:&lt;/i&gt;&lt;/b&gt; To establish a clinical interpretation of the Skin Cancer Quality of Life questionnaire (SCQoL), a newly validated HRQoL instrument for patients with non-melanoma skin cancer (NMSC), using an anchor-based method, and to test the responsiveness. &lt;b&gt;&lt;i&gt;Methods:&lt;/i&gt;&lt;/b&gt; Receiver-operating characteristic analysis was used to propose clinically meaningful cut-off scores for SCQoL including 101 patients with NMSC. &lt;b&gt;&lt;i&gt;Results:&lt;/i&gt;&lt;/b&gt; The following bands were established: score 0-3 corresponds to no impairment, 4-6 corresponds to mild impairment, 7-10 to moderate impairment and 11-27 to severe impairment of HRQoL. Testing the responsiveness shows a moderate effect size and significantly lower scores only for the domain emotion and the global item. &lt;b&gt;&lt;i&gt;Conclusion:&lt;/i&gt;&lt;/b&gt; Using proposed clinical cut-off scores for SCQoL may help clinicians in their decision-making, help monitoring clinical improvement and classify patients just as e.g. the Dermatology Life Quality Index can.</jats:p>