Beschreibung:
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<jats:bold>Introduction:</jats:bold>
Data on health-related quality of life (HRQOL) of resuscitated out-of-hospital cardiac arrest (OHCA) patients remain scarce. Our aims were to compare long-term HRQOL of OHCA with that of the general population, and to assess factors associated with better HRQOL.
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<jats:bold>Methods:</jats:bold>
We used a large cohort of OHCA patients admitted in a tertiary medical intensive care unit. The main outcome was HRQOL (SF-36 questionnaire). Each OHCA case was matched with 4 controls of same age and sex issued from general French population. The associations between pre and intra hospital variables and early interventions with the SF-36 dimensions were investigated using MANCOVA.
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<jats:bold>Results:</jats:bold>
During the study period (2000-2013), 1829 OHCA patients were admitted and 602 have been discharged alive. SF-36 interview took place 50 [22-93] months after OHCA. Between discharge and the interview, 137 patients died, 210 were lost of follow-up and then 255 (median age 55 [45,64] y., mostly male (73.7%)) were interviewed. Initial rhythm was shockable in 210 (82.4%) cases. Global physical and mental components did not differ between OHCA survivors and general population (47.0 vs. 47.1, p=0.88 and 46.4 vs. 46.9, p=0.45). However, physical functioning and vitality were significantly altered in OHCA survivors (Figure. SF-36 dimensions of 255 OHCA patients (grey rectangles) and of matched controls (black circles)). Younger age and male gender were independently associated with almost all SF-36 dimensions. Initial VF/VT was associated with a gain in most of the SF-36 dimensions. Successful PCI was associated with a gain in physical functioning (+7.0, p=0.06) and in general health (+7.3, p=0.02) and in vitality (+4.4, p=0.08).
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<jats:bold>Conclusions:</jats:bold>
HRQOL of OHCA survivors appears similar to general population, but some physical components of SF36 scale were significantly altered. Younger age, male gender, initial shockable rhythm and coronary reperfusion were independently associated with a better HRQOL.
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