Beschreibung:
<jats:p>While transcutaneous continuous monitoring of partial pressure of oxygen (TcPO<jats:sub>2</jats:sub>) is a proven valuable diagnostic tool in intensive care of sick neonates, its use in older children is less well defined. The purpose of this study is to establish the accuracy and reliability of TcPo<jats:sub>2</jats:sub>as a reflection of arterial partial pressure of oxygen (Pao<jats:sub>2</jats:sub>) in critically ill pediatric patients. Twenty-six children, age ranging from 4 days to 13 years, were studied. The main diagnostic categories were cardiac 54 per cent, respiratory 27 per cent, gastrointestinal 15 per cent, and neurologic 4 per cent. Forty three estimations of Pa<jats:sub>o2</jats:sub>(by radial arterial sampling) and TcPO<jats:sub>2</jats:sub>(by cutaneous monitor) were obtained simultaneously. Their correlation coefficient, regression equation, and confidence limits were calculated by standard statistical methods with the aid of a microcomputer. Our data show that the high degree of correlation between TcPO<jats:sub>2</jats:sub>and Pa<jats:sub>o2</jats:sub>is highly significant (r = 0.90, p < 0.001) for the full range of Pa<jats:sub>o2</jats:sub>between 0 to 200 mm Hg. At the lower range of Pa<jats:sub>o2</jats:sub>(0-79 mm Hg), the degree of correlation (r = 0.91, p < 0.001) is better than that (r = 0.77, p < 0.001) at the higher range (80-200 mm Hg), although the difference between the two correlation coefficients is not significant (p > 0.05). It is important to note that TcPo<jats:sub>2</jats:sub>consistently underestimates the Pa<jats:sub>o2</jats:sub>and the 95% confidence limits are rather wide. We conclude that TcPO<jats:sub>2</jats:sub>is a reasonably accurate reflection of Pa<jats:sub>o2</jats:sub>in critically ill pediatric patients. Its main advantage is in predicting and showing trends in tissue oxygenation by noninvasive means. However, when critical assessment of the degree of hypoxemia is required, TcPO<jats:sub>2</jats:sub>is no substitute for Pa<jats:sub>o2</jats:sub>.</jats:p>