• Medientyp: E-Artikel
  • Titel: Antiviral activity of sirolimus in an HIV-positive kidney transplant recipient
  • Beteiligte: Alfano, Gaetano; Fontana, Francesco; Mori, Giacomo; Vicari, Emanuela; Dolci, Giovanni; Franceschini, Erica; Guaraldi, Giovanni; Mussini, Cristina; Cappelli, Gianni
  • Erschienen: SAGE Publications, 2019
  • Erschienen in: International Journal of STD & AIDS
  • Sprache: Englisch
  • DOI: 10.1177/0956462419839520
  • ISSN: 0956-4624; 1758-1052
  • Schlagwörter: Infectious Diseases ; Pharmacology (medical) ; Public Health, Environmental and Occupational Health ; Dermatology
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  • Beschreibung: <jats:p> Sirolimus (SIR) is a potent immunosuppressive agent with multiple proprieties. We report beneficial antiviral effects of SIR in an HIV-positive kidney transplant recipient who experienced low-level HIV-1 replication. The immunosuppressive agent was well tolerated by the patient, and no side effects were reported during follow-up. Despite immunosuppressive monotherapy, SIR ensured stable graft function. </jats:p>