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Medientyp:
E-Artikel
Titel:
Granulomatous rhinitis due to Candida parapsilosis in a cat
Beteiligte:
Lamm, Catherine G.;
Grune, Sterrett C.;
Estrada, Marko M.;
McIlwain, Mary B.;
Leutenegger, Christian M.
Erschienen:
SAGE Publications, 2013
Erschienen in:
Journal of Veterinary Diagnostic Investigation, 25 (2013) 5, Seite 596-598
Sprache:
Englisch
DOI:
10.1177/1040638713495388
ISSN:
1040-6387;
1943-4936
Entstehung:
Anmerkungen:
Beschreibung:
A 9-year-old female spayed Domestic Medium Hair cat presented to the referring veterinarian with a 2-week history of sneezing, which progressed to swelling over the nasal planum. The cat had been under veterinary care for inflammatory bowel disease and had been treated with 1.25 mg/kg prednisolone once a day for approximately 1 year. On physical examination, an approximately 2–3 mm diameter, round polypoid pink soft-tissue mass was protruding slightly from the right nostril. Through histologic examination of representative sections from the mass, there was a severe diffuse infiltrate of epithelioid macrophages and neutrophils that surrounded frequent 15–20 µm yeast organisms. A Grocott methenamine silver stain revealed the presence of pseudohyphae in addition to the previously noted yeast forms. Real-time polymerase chain reaction (PCR) for Cryptococcus neoformans, Ajellomyces dermatitidis (syn. Blastomyces dermatitidis), Coccidioides immitis, Ajellomyces capsulatus (syn. Histoplasma capsulatum), Malassezia spp., and Candida spp. was performed on the paraffin-embedded sample. The PCR for Candida spp. was positive; the product was then sequenced and was determined to be consistent with Candida parapsilosis. Following the PCR diagnosis and prior to treatment of the infection, C. parapsilosis was cultured from a nasal swab. The infection in the cat in the current report was considered opportunistic and secondary to immunosuppression, following treatment for the inflammatory bowel disease.