Beschreibung:
<jats:sec><jats:title>Background:</jats:title><jats:p> COVID-19 mortality risk factors have been established in large cohort studies; long-term mortality outcomes are less documented. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> We performed multivariable logistic regression to identify factors associated with in-patient mortality and intensive care unit (ICU) admission in symptomatic COVID-19 patients admitted to hospitals in South-East Scotland from 1st March to 30th June 2020. One-year mortality was reviewed. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> Of 726 patients (median age 72; interquartile range: 58–83 years, 55% male), 104 (14%) required ICU admission and 199 (27%) died in hospital. A further 64 died between discharge and 30th June 2021 (36% overall 1-year mortality). Stepwise logistic regression identified age >79 (odds ratio (OR), 4.77 (95% confidence interval (CI), 1.96–12.75)), male sex (OR, 1.83 (95% CI, 1.21–2.80)) and higher European Cooperative Oncology Group/World Health Organization performance status as associated with higher mortality risk. </jats:p></jats:sec><jats:sec><jats:title>Discussion:</jats:title><jats:p> Poor functional baseline was the predominant independent risk factor for mortality in COVID-19. More than one-third of individuals had died by 1 year following admission. </jats:p></jats:sec>