Erschienen in:
Blood Advances, 2 (2018) 5, Seite 470-480
Sprache:
Englisch
DOI:
10.1182/bloodadvances.2017010868
ISSN:
2473-9529;
2473-9537
Entstehung:
Anmerkungen:
Beschreibung:
Key PointsFibrosis in the liver is a common cause of liver disease, partially mediated by platelet TGF-β1 as shown in a mouse model of liver injury. Depleting platelet TGF-β1 results in decreased liver fibrosis suggesting that blocking platelet TGF-β1 may ameliorate or prevent fibrosis.