• Medientyp: E-Artikel
  • Titel: Daratumumab in life-threatening autoimmune hemolytic anemia following hematopoietic stem cell transplantation
  • Beteiligte: Schuetz, Catharina; Hoenig, Manfred; Moshous, Despina; Weinstock, Christof; Castelle, Martin; Bendavid, Matthieu; Shimano, Kristin; Tolbert, Vanessa; Schulz, Ansgar S.; Dvorak, Christopher C.
  • Erschienen: American Society of Hematology, 2018
  • Erschienen in: Blood Advances, 2 (2018) 19, Seite 2550-2553
  • Sprache: Englisch
  • DOI: 10.1182/bloodadvances.2018020883
  • ISSN: 2473-9529; 2473-9537
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  • Beschreibung: Abstract New-onset autoimmune hemolytic anemia (AIHA) occurs in 2% to 6% of pediatric patients post–hematopoietic stem cell transplantation (HSCT) and is a significant complication. Incomplete immune recovery following HSCT may predispose to immune dysregulation including autoimmune cytopenias. We describe an innovative therapy for AIHA refractory to proteasome inhibition. In potentially life-threatening AIHA in the context of HSCT, daratumumab may be an effective rescue therapy.
  • Zugangsstatus: Freier Zugang