Sie können Bookmarks mittels Listen verwalten, loggen Sie sich dafür bitte in Ihr SLUB Benutzerkonto ein.
Medientyp:
E-Artikel
Titel:
Oxalate nephropathy after pancreaticoduodenectomy: a case report
Beteiligte:
Barani, Claire;
Aydin, Selda;
Demoulin, Nathalie;
Jadoul, Michel
Erschienen:
Springer Science and Business Media LLC, 2024
Erschienen in:
BMC Nephrology, 25 (2024) 1
Sprache:
Englisch
DOI:
10.1186/s12882-024-03543-9
ISSN:
1471-2369
Entstehung:
Anmerkungen:
Beschreibung:
AbstractA 75-year-old male developed acute kidney injury KDIGO stage 3 a few weeks after Whipple surgery was performed for a distal cholangiocarcinoma. Kidney biopsy revealed oxalate nephropathy. This was attributed to post-Whipple malabsorption, poor compliance with pancreatic enzyme replacement therapy, and daily intake of vitamin C supplements. Pancreatic enzyme replacement therapy was resumed and calcium carbonate initiated, with an improvement in glomerular filtration rate. Unfortunately, due to oncological progression, best supportive care was initiated.We review the pathophysiology and conditions predisposing to secondary hyperoxaluria and oxalate nephropathy. This diagnosis should be considered among the main causes of acute kidney injury following pancreatectomy, with important therapeutic implications.