> Detailanzeige

Lombardi, Francesco; Calabrese, Angelo; Iovene, Bruno; Pierandrei, Chiara; Lerede, Marialessia; Varone, Francesco; Richeldi, Luca; Sgalla, Giacomo; Landi, Francesco; Gremese, Elisa; Bernabei, Roberto; Fantoni, Massimo; Gasbarrini, Antonio; Romano Settanni, Carlo; Benvenuto, Francesca; Bramato, Giulia; Carfì, Angelo; Ciciarello, Francesca; Rita Lo Monaco, Maria; Maria Martone, Anna; Marzetti, Emanuele; Napolitano, Carmen; Pagano, Francesco; Rocchi, Sara; [...]

Residual respiratory impairment after COVID-19 pneumonia

Literatur-
verwaltung

Zur
Merkliste

Lösche von
Merkliste

Per Whatsapp teilen

Schließen

Merkliste



Sie können Bookmarks mittels Listen verwalten, loggen Sie sich dafür bitte in Ihr SLUB Benutzerkonto ein.
  • Medientyp: E-Artikel
  • Titel: Residual respiratory impairment after COVID-19 pneumonia
  • Beteiligte: Lombardi, Francesco; Calabrese, Angelo; Iovene, Bruno; Pierandrei, Chiara; Lerede, Marialessia; Varone, Francesco; Richeldi, Luca; Sgalla, Giacomo; Landi, Francesco; Gremese, Elisa; Bernabei, Roberto; Fantoni, Massimo; Gasbarrini, Antonio; Romano Settanni, Carlo; Benvenuto, Francesca; Bramato, Giulia; Carfì, Angelo; Ciciarello, Francesca; Rita Lo Monaco, Maria; Maria Martone, Anna; Marzetti, Emanuele; Napolitano, Carmen; Pagano, Francesco; Rocchi, Sara; [...]
  • Erschienen: Springer Science and Business Media LLC, 2021
  • Erschienen in: BMC Pulmonary Medicine
  • Sprache: Englisch
  • DOI: 10.1186/s12890-021-01594-4
  • ISSN: 1471-2466
  • Schlagwörter: Pulmonary and Respiratory Medicine
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:title>Abstract</jats:title><jats:sec> <jats:title>Introduction</jats:title> <jats:p>The novel coronavirus SARS-Cov-2 can infect the respiratory tract causing a spectrum of disease varying from mild to fatal pneumonia, and known as COVID-19. Ongoing clinical research is assessing the potential for long-term respiratory sequelae in these patients. We assessed the respiratory function in a cohort of patients after recovering from SARS-Cov-2 infection, stratified according to PaO<jats:sub>2</jats:sub>/FiO<jats:sub>2</jats:sub> (p/F) values.</jats:p> </jats:sec><jats:sec> <jats:title>Method</jats:title> <jats:p>Approximately one month after hospital discharge, 86 COVID-19 patients underwent physical examination, arterial blood gas (ABG) analysis, pulmonary function tests (PFTs), and six-minute walk test (6MWT). Patients were also asked to quantify the severity of dyspnoea and cough before, during, and after hospitalization using a visual analogic scale (VAS). Seventy-six subjects with ABG during hospitalization were stratified in three groups according to their worst p/F values: above 300 (n = 38), between 200 and 300 (n = 30) and below 200 (n = 20).</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>On PFTs, lung volumes were overall preserved yet, mean percent predicted residual volume was slightly reduced (74.8 ± 18.1%). Percent predicted diffusing capacity for carbon monoxide (DLCO) was also mildly reduced (77.2 ± 16.5%). Patients reported residual breathlessness at the time of the visit (VAS 19.8, p &lt; 0.001). Patients with p/F below 200 during hospitalization had lower percent predicted forced vital capacity (p = 0.005), lower percent predicted total lung capacity (p = 0.012), lower DLCO (p &lt; 0.001) and shorter 6MWT distance (p = 0.004) than patients with higher p/F.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>Approximately one month after hospital discharge, patients with COVID-19 can have residual respiratory impairment, including lower exercise tolerance. The extent of this impairment seems to correlate with the severity of respiratory failure during hospitalization.</jats:p> </jats:sec>
  • Zugangsstatus: Freier Zugang