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Pazukhina, Ekaterina; Andreeva, Margarita; Spiridonova, Ekaterina; Bobkova, Polina; Shikhaleva, Anastasia; El-Taravi, Yasmin; Rumyantsev, Mikhail; Gamirova, Aysylu; Bairashevskaia, Anastasiia; Petrova, Polina; Baimukhambetova, Dina; Pikuza, Maria; Abdeeva, Elina; Filippova, Yulia; Deunezhewa, Salima; Nekliudov, Nikita; Bugaeva, Polina; Bulanov, Nikolay; Avdeev, Sergey; Kapustina, Valentina; Guekht, Alla; DunnGalvin, Audrey; Comberiati, Pasquale; Peroni, Diego G.; [...]

Prevalence and risk factors of post-COVID-19 condition in adults and children at 6 and 12 months after hospital discharge: a prospective, cohort study in Moscow (StopCOVID)

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  • Medientyp: E-Artikel
  • Titel: Prevalence and risk factors of post-COVID-19 condition in adults and children at 6 and 12 months after hospital discharge: a prospective, cohort study in Moscow (StopCOVID)
  • Beteiligte: Pazukhina, Ekaterina; Andreeva, Margarita; Spiridonova, Ekaterina; Bobkova, Polina; Shikhaleva, Anastasia; El-Taravi, Yasmin; Rumyantsev, Mikhail; Gamirova, Aysylu; Bairashevskaia, Anastasiia; Petrova, Polina; Baimukhambetova, Dina; Pikuza, Maria; Abdeeva, Elina; Filippova, Yulia; Deunezhewa, Salima; Nekliudov, Nikita; Bugaeva, Polina; Bulanov, Nikolay; Avdeev, Sergey; Kapustina, Valentina; Guekht, Alla; DunnGalvin, Audrey; Comberiati, Pasquale; Peroni, Diego G.; [...]
  • Erschienen: Springer Science and Business Media LLC, 2022
  • Erschienen in: BMC Medicine
  • Sprache: Englisch
  • DOI: 10.1186/s12916-022-02448-4
  • ISSN: 1741-7015
  • Schlagwörter: General Medicine
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Previous studies assessing the prevalence of COVID-19 sequelae in adults and children were performed in the absence of an agreed definition. We investigated prevalence of post-COVID-19 condition (PCC) (WHO definition), at 6- and 12-months follow-up, amongst previously hospitalised adults and children and assessed risk factors.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>Prospective cohort study of children and adults with confirmed COVID-19 in Moscow, hospitalised between April and August, 2020. Two follow-up telephone interviews, using the International Severe Acute Respiratory and Emerging Infection Consortium survey, were performed at 6 and 12 months after discharge.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>One thousand thirteen of 2509 (40%) of adults and 360 of 849 (42%) of children discharged participated in both the 6- and 12-month follow-ups. PCC prevalence was 50% (95% CI 47–53) in adults and 20% (95% CI 16–24) in children at 6 months, with decline to 34% (95% CI 31–37) and 11% (95% CI 8–14), respectively, at 12 months. In adults, female sex was associated with PCC at 6- and 12-month follow-up (OR 2.04, 95% CI 1.57 to 2.65) and (OR 2.04, 1.54 to 2.69), respectively. Pre-existing hypertension (OR 1.42, 1.04 to 1.94) was associated with post-COVID-19 condition at 12 months. In children, neurological comorbidities were associated with PCC both at 6 months (OR 4.38, 1.36 to 15.67) and 12 months (OR 8.96, 2.55 to 34.82) while allergic respiratory diseases were associated at 12 months (OR 2.66, 1.04 to 6.47).</jats:p> </jats:sec><jats:sec> <jats:title>Conclusions</jats:title> <jats:p>Although prevalence of PCC declined one year after discharge, one in three adults and one in ten children experienced ongoing sequelae. In adults, females and persons with pre-existing hypertension, and in children, persons with neurological comorbidities or allergic respiratory diseases are at higher risk of PCC.</jats:p> </jats:sec>
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