Bednarsch, Jan;
Czigany, Zoltan;
Heise, Daniel;
Zimmermann, Henning;
Boecker, Joerg;
Ulmer, Tom Florian;
Neumann, Ulf Peter;
Klink, Christian
Influence of peritoneal carcinomatosis on perioperative outcome in palliative gastric bypass for malignant gastric outlet obstruction - a retrospective cohort study
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Medientyp:
E-Artikel
Titel:
Influence of peritoneal carcinomatosis on perioperative outcome in palliative gastric bypass for malignant gastric outlet obstruction - a retrospective cohort study
Beteiligte:
Bednarsch, Jan;
Czigany, Zoltan;
Heise, Daniel;
Zimmermann, Henning;
Boecker, Joerg;
Ulmer, Tom Florian;
Neumann, Ulf Peter;
Klink, Christian
Erschienen:
Springer Science and Business Media LLC, 2020
Erschienen in:
World Journal of Surgical Oncology, 18 (2020) 1
Sprache:
Englisch
DOI:
10.1186/s12957-020-1803-5
ISSN:
1477-7819
Entstehung:
Anmerkungen:
Beschreibung:
AbstractBackgroundMalignant gastric outlet obstruction (GOO) is commonly associated with the presence of peritoneal carcinomatosis (PC) and preferably treated by surgical gastrojejunostomy (GJJ) in patients with good performance. Here, we aim to investigate the role of PC as a risk factor for perioperative morbidity and mortality in patients with GOO undergoing GJJ.MethodsPerioperative data of 72 patients with malignant GOO who underwent palliative GJJ at our institution between 2010 and 2019 were collected within an institutional database.To compare perioperative outcomes of patients with and without PC, extensive group analyses were carried out.ResultsA set of 39 (54.2%) patients was histologically diagnosed with concomitant PC while the remaining 33 (45.8%) patients showed no clinical signs of PC. In-house mortality due to surgical complications was significantly higher in patients with PC (9/39, 23.1%) than in patients without PC (2/33, 6.1%,p= .046). Considerable differences were observed in terms of surgical complications such as anastomotic leakage rates (2.8% vs. 0%,p= .187), delayed gastric emptying (33.3% vs. 15.2%,p= .076), paralytic ileus (23.1% vs. 9.1%,p= .113), and pneumonia (17.9% vs. 12.1%,p= .493) without reaching the level of statistical significance.ConclusionsPC is an important predictor of perioperative morbidity and mortality patients undergoing GJJ for malignant GOO.