Beschreibung:
<jats:title>Abstract</jats:title><jats:sec>
<jats:title>Background</jats:title>
<jats:p>Praziquantel is the drug of choice for treating the tapeworm <jats:italic>Dipylidium caninum</jats:italic> in dogs; however, resistance is possible, and regular, non-targeted administration of praziquantel may select for anthelminthic-resistant populations.</jats:p>
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<jats:title>Methods</jats:title>
<jats:p>The zinc sulfate fecal floatation procedure was conducted. Gross visualization was used to identify <jats:italic>Dipylidium</jats:italic> spp. segments, and capsule endoscopy was used to visualize adult tapeworms within the intestinal tract.</jats:p>
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<jats:title>Results</jats:title>
<jats:p>An 18-month-old spayed female terrier mix was presented due to diarrhea, hematochezia and weight loss. The dog received appropriate anthelmintic therapy for <jats:italic>Giardia</jats:italic> spp., <jats:italic>Ancylostoma</jats:italic> spp. and <jats:italic>Dipylidium</jats:italic> spp. The dog’s clinical signs resolved, and elimination of <jats:italic>Ancylostoma</jats:italic> spp. was confirmed by subsequent fecal analysis. However, <jats:italic>Dipylidium</jats:italic> spp. segments were repeatedly present in the stool. Observation of the segments confirmed the presence of adult <jats:italic>Dipylidium</jats:italic> spp in feces. Treatment with praziquantel and epsiprantel were unsuccessful in eliminating the organism but was apparently successful in flea prevention. A single dose of nitrosconate was administered and eliminated <jats:italic>Dipylidium</jats:italic> spp. infection in the dog.</jats:p>
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<jats:title>Conclusions</jats:title>
<jats:p>Nitrosconate can be an effective treatment for praziquantel-resistant dipylidiasis in dogs. The novel application of capsule endoscopy confirmed the anthelmintic efficacy of this treatment.</jats:p>
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<jats:title>Graphical Abstract</jats:title>
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