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Medientyp:
E-Artikel
Titel:
N,N-Dimethylglycine in patients with progressive multiple sclerosis: result of a pilot double-blind, placebo, controlled randomized clinical trial
Beteiligte:
Wolfsegger, Thomas;
Böck, Klaus;
Schimetta, Wolfgang;
von Oertzen, Tim J.;
Assar, Hamid
Erschienen:
Springer Science and Business Media LLC, 2021
Erschienen in:
Neurological Research and Practice, 3 (2021) 1
Sprache:
Englisch
DOI:
10.1186/s42466-021-00126-z
ISSN:
2524-3489
Entstehung:
Anmerkungen:
Beschreibung:
AbstractOral administration of N,N-Dimethylglycine (DMG), a tertiary amino acid, presumably enhances oxygen utilization by tissue and complex with free radicals. Beneficial effects are improved endurance performance and reduction fatigue in humans and animals. This pilot study reports the results over a one-year double-blind, placebo-controlled trial of DMG in 30 randomized patients with progressive multiple sclerosis. No treatment effects were found between the placebo group and the DMG group for disability, fatigue, cognitive, or gait parameters.