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Weinstock-Guttman, B; Jacobs, L D; Brownscheidle, C M; Baier, M; Rea, D F; Apatoff, B R; Blitz, K M; Coyle, P K; Frontera, A T; Goodman, A D; Gottesman, M H; Herbert, J; Holub, R; Lava, N S; Lenihan, M; Lusins, J; Mihai, C; Miller, A E; Perel, A B; Snyder, D H; Bakshi, R; Granger, C V; Greenberg, S J; Jubelt, B; [...]

Multiple sclerosis characteristics in A frican A merican patients in the New York State Multiple Sclerosis C onsortium

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  • Medientyp: E-Artikel
  • Titel: Multiple sclerosis characteristics in A frican A merican patients in the New York State Multiple Sclerosis C onsortium
  • Beteiligte: Weinstock-Guttman, B; Jacobs, L D; Brownscheidle, C M; Baier, M; Rea, D F; Apatoff, B R; Blitz, K M; Coyle, P K; Frontera, A T; Goodman, A D; Gottesman, M H; Herbert, J; Holub, R; Lava, N S; Lenihan, M; Lusins, J; Mihai, C; Miller, A E; Perel, A B; Snyder, D H; Bakshi, R; Granger, C V; Greenberg, S J; Jubelt, B; [...]
  • Erschienen: SAGE Publications, 2003
  • Erschienen in: Multiple Sclerosis Journal, 9 (2003) 3, Seite 293-298
  • Sprache: Englisch
  • DOI: 10.1191/1352458503ms909oa
  • ISSN: 1352-4585; 1477-0970
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: The objective of this study was to determine the clinical characteristics of multiple sclerosis (MS) in A frican A merican (A A) patients in the New York State Multiple Sclerosis C onsortium (NYSMSC) patient registry. The NYSMSC is a group of 18 MS centers throughout New York State organized to prospectively assess clinical characteristics of MS patients. AA s comprise 6% (329) of the total NYSMSC registrants (5602). Demographics, disease course, therapy, and socioeconomic status were compared in A A registrants versus nonA frican A mericans (NA A). There was an increased female preponderance and a significantly younger age at diagnosis in the AA group. A A patients were more likely to have greater disability with increased disease duration. No differences were seen in types of MS and use of disease modifying therapies. O ur findings suggest a racial influence in MS. Further genetic studies that consider race differences are warranted to elucidate mechanisms of disease susceptibility.