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Lassaline‐Utter, Mary; Cutler, Tim J.; Michau, Tammy M.; Nunnery, Catherine M.

Treatment of nonhealing corneal ulcers in 60 horses with diamond burr debridement (2010–2013)

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  • Medientyp: E-Artikel
  • Titel: Treatment of nonhealing corneal ulcers in 60 horses with diamond burr debridement (2010–2013)
  • Beteiligte: Lassaline‐Utter, Mary; Cutler, Tim J.; Michau, Tammy M.; Nunnery, Catherine M.
  • Erschienen: Wiley, 2014
  • Erschienen in: Veterinary Ophthalmology
  • Sprache: Englisch
  • DOI: 10.1111/vop.12148
  • ISSN: 1463-5216; 1463-5224
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:title>Abstract</jats:title><jats:sec><jats:title>Objective</jats:title><jats:p>To review the signalment, clinical characteristics, and outcome of horses with nonhealing corneal ulcers treated with diamond burr debridement (<jats:styled-content style="fixed-case">DBD</jats:styled-content>); and to evaluate the role of ulcer duration, size and location, and bandage contact lens (<jats:styled-content style="fixed-case">BCL</jats:styled-content>) placement on healing.</jats:p></jats:sec><jats:sec><jats:title>Animals</jats:title><jats:p>From January 2012–April 2013, 60 horses were diagnosed with ulcers classified as nonhealing based on the presence of raised epithelial margins and duration of at least 7 days.</jats:p></jats:sec><jats:sec><jats:title>Procedure</jats:title><jats:p>Retrospective record review.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Average age of included horses was 14.68 years, <jats:styled-content style="fixed-case">SD</jats:styled-content> 8.17 years. There were three times as many males (45) as females (15), (<jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/vop12148-math-0001.gif" xlink:title="urn:x-wiley:14635216:media:vop12148:vop12148-math-0001" /> = 15, <jats:italic>P</jats:italic> = 0.001). Forty‐eight horses (80%) had nonhealing ulcers uncomplicated by associated corneal disease. In the remaining horses, associated corneal disease included esinophilic keratitis (10%), calcific band keratopathy (5%), endothelial decompensation (1.67%), habronemiasis(1.67%), and lid suture abrasion (1.67%). Average corneal ulcer duration prior to diamond burr debridement (<jats:styled-content style="fixed-case">DBD</jats:styled-content>) was 29.0 days (<jats:italic>n</jats:italic> = 56). Ulcers occurred most commonly in the axial cornea (41%). Fifty‐five of 60 horses (92%) healed with <jats:styled-content style="fixed-case">DBD</jats:styled-content>. Healing time, defined as time to epithelialization following <jats:styled-content style="fixed-case">DBD</jats:styled-content>, averaged 15.5 days, <jats:styled-content style="fixed-case">SD</jats:styled-content> 9.32 days, and was not correlated with patient age or ulcer duration, location, or size prior to or following <jats:styled-content style="fixed-case">DBD</jats:styled-content>. Healing time was significantly longer for eyes in which a <jats:styled-content style="fixed-case">BCL</jats:styled-content> had been placed (<jats:italic>n</jats:italic> = 28, 19.0 days) than for eyes without a <jats:styled-content style="fixed-case">BCL</jats:styled-content> (<jats:italic>n</jats:italic> = 32, 12.9 days), <jats:italic>F</jats:italic>(1,58) = 5.543, <jats:italic>P</jats:italic> = 0.02. <jats:styled-content style="fixed-case">DBD</jats:styled-content> was considered a failure for five horses (8%).</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p><jats:styled-content style="fixed-case">DBD</jats:styled-content> may be an effective treatment for nonhealing corneal ulcers in horses.</jats:p></jats:sec>