• Medientyp: E-Artikel
  • Titel: Quality of life in stable and progressive ‘early‐stage’ keratoconus patients
  • Beteiligte: Steinberg, Johannes; Bußmann, Nils; Frings, Andreas; Katz, Toam; Druchkiv, Vasyl; Linke, Stephan J.
  • Erschienen: Wiley, 2021
  • Erschienen in: Acta Ophthalmologica, 99 (2021) 2
  • Sprache: Englisch
  • DOI: 10.1111/aos.14564
  • ISSN: 1755-375X; 1755-3768
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:title>Abstract</jats:title><jats:sec><jats:title>Purpose</jats:title><jats:p>To analyse the vision‐related quality of life (vr‐QoL) in stable and progressive keratoconus (KC) patients with a still good visual acuity.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Combined prospective/cross‐sectional study design. The Refractive Status and Vision Profile (RSVP) and the National Eye Institute Visual Functioning – 25 (NEI‐25) questionnaire were used in 16 emmetropic, 32 myopic and 56 KC patients, whereby KC patients with a stable (<jats:italic>n</jats:italic> = 26) and patients with a progressive stage (<jats:italic>n</jats:italic> = 30) and some of them before and after corneal cross‐linking (CXL; <jats:italic>n</jats:italic> = 10) were included. All patients had a DCVA in at least one eye of ≥0.7 (decimal chart).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The analyses revealed a minor decline of the vr‐QoL from emmetropes to myopes to early KC patients with a stable disease. Nonetheless, sociological subscales (i.e. ‘social functioning’, ‘role difficulties’ and ‘dependency’) did not display statistically significant differences comparing these groups. In progressive KC, we could demonstrate a statistically significant decline also of these sociological subscales, which did not improve after CXL.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Due to a still high and almost unaffected vr‐QoL in early KC patients and the distinct decline after progression without rehabilitation after CXL, a reconsideration of current strategies to perform CXL only after a progression is diagnosed should be re‐evaluated.</jats:p></jats:sec>
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