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Oei, Ju Lee; Ghadge, Alpana; Coates, Elisabeth; Wright, Ian M.; Saugstad, Ola D.; Vento, Maximo; Buonocore, Giuseppe; Nagashima, Tatsuo; Suzuki, Keiji; Hosono, Shiguhero; Davis, Peter G.; Craven, Paul; Askie, Lisa; Dawson, Jennifer; Garg, Shalabh; Keech, Anthony; Rabi, Yacov; Smyth, John; Sinha, Sunil; Stenson, Ben; Lui, Kei; Hunter, Carol Lu; Tarnow Mordi, William

Clinicians in 25 countries prefer to use lower levels of oxygen to resuscitate preterm infants at birth

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  • Medientyp: E-Artikel
  • Titel: Clinicians in 25 countries prefer to use lower levels of oxygen to resuscitate preterm infants at birth
  • Beteiligte: Oei, Ju Lee; Ghadge, Alpana; Coates, Elisabeth; Wright, Ian M.; Saugstad, Ola D.; Vento, Maximo; Buonocore, Giuseppe; Nagashima, Tatsuo; Suzuki, Keiji; Hosono, Shiguhero; Davis, Peter G.; Craven, Paul; Askie, Lisa; Dawson, Jennifer; Garg, Shalabh; Keech, Anthony; Rabi, Yacov; Smyth, John; Sinha, Sunil; Stenson, Ben; Lui, Kei; Hunter, Carol Lu; Tarnow Mordi, William
  • Erschienen: Wiley, 2016
  • Erschienen in: Acta Paediatrica
  • Sprache: Englisch
  • DOI: 10.1111/apa.13485
  • ISSN: 1651-2227; 0803-5253
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:title>Abstract</jats:title><jats:sec><jats:title>Aim</jats:title><jats:p>This study determined current international clinical practice and opinions regarding initial fractional inspired oxygen (FiO<jats:sub>2</jats:sub>) and pulse oximetry (SpO<jats:sub>2</jats:sub>) targets for delivery room resuscitation of preterm infants of less than 29 weeks of gestation.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>An online survey was disseminated to neonatal clinicians via established professional clinical networks using a web‐based survey programme between March 9 and June 30, 2015.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Of the 630 responses from 25 countries, 60% were from neonatologists. The majority (77%) would target SpO<jats:sub>2</jats:sub> between the 10th to 50th percentiles values for full‐term infants. The median starting FiO<jats:sub>2</jats:sub> was 0.3, with Japan using the highest (0.4) and the <jats:styled-content style="fixed-case">UK</jats:styled-content> using the lowest (0.21). New Zealand targeted the highest SpO<jats:sub>2</jats:sub> percentiles (median 50%). Most respondents agreed or did not disagree that a trial was required that compared the higher FiO<jats:sub>2</jats:sub> of 0.6 (83%), targeting the 50th SpO<jats:sub>2</jats:sub> percentile (60%), and the lower FiO<jats:sub>2</jats:sub> of 0.21 (80%), targeting the 10th SpO<jats:sub>2</jats:sub> percentile (78%). Most (65%) would join this trial. Many considered that evidence was lacking and further research was needed.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Clinicians currently favour lower SpO<jats:sub>2</jats:sub> targets for preterm resuscitation, despite acknowledging the lack of evidence for benefit or harm, and 65% would join a clinical trial.</jats:p></jats:sec>