Examining long‐term outcomes of bladder exstrophy: a 20‐year follow‐up

Medientyp: E-Artikel
Titel: Examining long‐term outcomes of bladder exstrophy: a 20‐year follow‐up
Beteiligte: Gupta, Angela D.; Goel, Sameer K.; Woodhouse, Christopher R.J.; Wood, Dan
Erschienen: Wiley, 2014
Erschienen in: BJU International
Sprache: Englisch
DOI: 10.1111/bju.12389
ISSN: 1464-4096; 1464-410X
Entstehung:
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Beschreibung: <jats:sec><jats:title>Objective</jats:title><jats:p><jats:list list-type="bullet"> <jats:list-item><jats:p>To examine long‐term quality‐of‐life, urinary continence and sexual function outcomes in patients diagnosed with bladder exstrophy (<jats:styled-content style="fixed-case">BE</jats:styled-content>).</jats:p></jats:list-item> </jats:list></jats:p></jats:sec><jats:sec><jats:title>Patients and Methods</jats:title><jats:p><jats:list list-type="bullet"> <jats:list-item><jats:p>A total of 65 patients with <jats:styled-content style="fixed-case">BE</jats:styled-content> and follow‐up of at least 20 years were identified.</jats:p></jats:list-item> <jats:list-item><jats:p>After informed consent for inclusion in the study, the patients were asked to complete three validated questionnaires, the Short‐Form 36 quality‐of‐life questionnaire (<jats:styled-content style="fixed-case">SF</jats:styled-content>‐36), the International Consultation on Incontinence Questionnaire (<jats:styled-content style="fixed-case">ICIQ</jats:styled-content>) and the International Index of Erectile Function (<jats:styled-content style="fixed-case">IIEF</jats:styled-content>), to assess quality of life, perceived urinary continence and sexual function.</jats:p></jats:list-item> </jats:list></jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p><jats:list list-type="bullet"> <jats:list-item><jats:p>In all, 21 patients responded to the questionnaires, yielding a 32% response rate.</jats:p></jats:list-item> <jats:list-item><jats:p>High scores in each of the eight dimensions of the <jats:styled-content style="fixed-case">SF</jats:styled-content>‐36 reflected a positive perception of quality of life by respondents; calculated scores were compared with those of a normal control group. The only significant difference found between the groups was that the study population perceived their general health to be poorer than those in the control group.</jats:p></jats:list-item> <jats:list-item><jats:p>High scores on the <jats:styled-content style="fixed-case">ICIQ</jats:styled-content> indicate high levels of subjective incontinence in patients, with scores ranging from 0 to 21. Reporting scores of 0 (continent), 12/21 patients perceived their continence to be normal, 9/21 patients had scores >2 (mild), with one patient scoring a 16, and 11 (severe incontinence), patients reported no identifiable leakage during normal activities.</jats:p></jats:list-item> <jats:list-item><jats:p>There was a 29% response rate for the <jats:styled-content style="fixed-case">IIEF</jats:styled-content> (15 patients completed this). <jats:styled-content style="fixed-case">IIEF</jats:styled-content> scores were broken down into five dimensions and mean scores were calculated. The mean scores showed mild to moderate dysfunction in each category, including overall satisfaction with sexual experience.</jats:p></jats:list-item> </jats:list></jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p><jats:list list-type="bullet"> <jats:list-item><jats:p>The patient‐reported quality of life in patients with <jats:styled-content style="fixed-case">BE</jats:styled-content> was normal in all dimensions, with the exception of perception of general health. Half of the patients reported normal continence and had no complaints of urinary leakage.</jats:p></jats:list-item> <jats:list-item><jats:p>Sexual function in males was significantly affected across all dimensions, with mild to moderate dysfunction.</jats:p></jats:list-item> </jats:list></jats:p></jats:sec>

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