• Medientyp: E-Artikel
  • Titel: Nonsebaceous lymphadenoma arising as a painless subcutaneous nodule on the eyebrow
  • Beteiligte: Calco, Gina N.; Davis, Jessica L.; Chung, Jina
  • Erschienen: Wiley, 2022
  • Erschienen in: Journal of Cutaneous Pathology
  • Sprache: Englisch
  • DOI: 10.1111/cup.14278
  • ISSN: 0303-6987; 1600-0560
  • Schlagwörter: Dermatology ; Histology ; Pathology and Forensic Medicine
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  • Beschreibung: <jats:title>Abstract</jats:title><jats:p>Salivary gland tumors can rarely present in skin excision specimens and can pose a diagnostic challenge to dermatopathologists. We present an exceptional case of a salivary gland type nonsebaceous lymphadenoma presenting as a painless subcutaneous nodule on the right medial eyebrow of a 16‐year‐old male, mimicking a primary cutaneous adnexal neoplasm. Histologic evaluation revealed a well‐circumscribed to partially encapsulated nodule with a marked lymphoid infiltrate including reactive germinal centers. Within the lymphoid component was a central epithelial cystic neoplasm with tubuloglandular and basaloid differentiation. There was no myoepithelial component to suggest a chondroid syringoma. No sebaceous differentiation was present. The overall histopathological and immunohistochemical findings were consistent with a nonsebaceous lymphadenoma. Dermatopathologists should consider salivary gland type lymphadenoma as a differential diagnosis when encountering a subcutaneous lesion with lymphoid, cystic, glandular, and basaloid components.</jats:p>