• Medientyp: E-Artikel
  • Titel: Rapid remineralization of multiple disseminated bone lesions after high‐dose cytarabine in a patient with isolated myeloid sarcoma
  • Beteiligte: Brähler, Sebastian; Thielen, Indra; Schwabe, Hendrik; Engels, Marianne; Kreuzer, Karl‐Anton; Wolf, Jürgen; Ansén, Sascha
  • Erschienen: Wiley, 2014
  • Erschienen in: European Journal of Haematology
  • Sprache: Englisch
  • DOI: 10.1111/ejh.12254
  • ISSN: 0902-4441; 1600-0609
  • Schlagwörter: Hematology ; General Medicine
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  • Beschreibung: <jats:title>Abstract</jats:title><jats:p>Isolated myeloid sarcoma is a rare presentation of acute myeloid leukemia. There are limited data available concerning the prognostic relevance and the right treatment strategy for this clinical scenario. Here, we report a case of acute myeloid leukemia with extensive lesions and fractures in multiple bones in a 64‐yr‐old male patient. Remarkably, treatment with a high‐dose cytarabine regimen led to rapid remineralization of all bone lesions and recovery of the patient's mobility within a few weeks. Thereby, surgical treatment and radiotherapy could be avoided, supporting the role of intensive induction and standard consolidation chemotherapy as first‐line treatment for myeloid sarcoma.</jats:p>