Beschreibung:
<jats:title>Abstract</jats:title><jats:p>Ichthyosis prematurity syndrome (IPS) is a rare type of syndromic autosomal recessive congenital ichthyosis (ARCI) caused by a mutation in the <jats:italic>SLC27A4</jats:italic> gene that encodes the fatty acid transport protein 4 (FATP4), which is responsible for keratinocyte differentiation and skin barrier function. IPS is characterized by a triad of prematurity, perinatal respiratory asphyxia, and thick vernix caseosa‐like scales. In this report, we present the clinical and molecular characterization of IPS in two Omani siblings.</jats:p>