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Medientyp:
E-Artikel
Titel:
T‐lymphocyte subsets in recurrent aphthous ulceration
Beteiligte:
Pedersen, Anne;
Klausen, Bjarne;
Hougen, Hans Petter;
Stenvang, Jens Peter
Erschienen:
Wiley, 1989
Erschienen in:
Journal of Oral Pathology & Medicine, 18 (1989) 1, Seite 59-60
Sprache:
Englisch
DOI:
10.1111/j.1600-0714.1989.tb00735.x
ISSN:
0904-2512;
1600-0714
Entstehung:
Anmerkungen:
Beschreibung:
Peripheral T‐lymphocyte subsets: T‐helper (OKT4) and T‐suppressor (OKT8) cells were studied quantitatively in 20 patients with recurrent aphthous ulceration (RAU) in ulcerative, as well as inactive, stages of the disease. The figures were compared with T‐lymphocyte subsets from matched control donors with no history of RAU. The ratio of T‐helper: T‐suppressor cells was significantly lower in both stages in the patients compared with controls due to a significantly increased number of T‐suppressor cells in RAU patients. The number of T‐helper cells in the patients did not differ significantly in either stage compared with controls. The study support the hypothesis of recurrent aphthous ulceration being a disorder of immunodeficiency.