• Medientyp: E-Artikel
  • Titel: X‐linked agammaglobulinemia complicated with endobronchial tuberculosis
  • Beteiligte: Kawakami, Chihiro; Inoue, Akiko; Takitani, Kimitaka; Kanegane, Hirokazu; Miyawaki, Toshio; Tamai, Hiroshi
  • Erschienen: Wiley, 2011
  • Erschienen in: Acta Paediatrica
  • Sprache: Englisch
  • DOI: 10.1111/j.1651-2227.2010.02071.x
  • ISSN: 0803-5253; 1651-2227
  • Schlagwörter: General Medicine ; Pediatrics, Perinatology and Child Health
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  • Beschreibung: <jats:title>Abstract</jats:title><jats:p><jats:bold>Aim: </jats:bold> We report a case of X‐linked agammaglobulinemia complicated with endobronchial tuberculosis.</jats:p><jats:p><jats:bold>Methods: </jats:bold> We observed the patient’s clinical course and analysed his data retrospectively.</jats:p><jats:p><jats:bold>Results:</jats:bold> Interestingly, the T‐cell proliferation activity in this patient was intact, and the CD4‐positive T cells produced interferon gamma. However, the result of the quantiferon alpha‐2b test was negative.</jats:p><jats:p><jats:bold>Conclusion: </jats:bold> The findings of this case suggest that the quantiferon alpha‐2b test may not be diagnostic for tuberculosis not only in patients with T‐cell disorders but also in cases with B‐cell deficiencies such as X‐linked agammaglobulinemia.</jats:p>