• Medientyp: E-Artikel
  • Titel: Comparison of sampling methods for profiling cervicovaginal microbiome in rhesus macaques
  • Beteiligte: Schmidt, Brian A.; Phillips, Ronald; Rolston, Matthew; Raeman, Reben; Iyer, Smita S.
  • Erschienen: Wiley, 2019
  • Erschienen in: Journal of Medical Primatology
  • Sprache: Englisch
  • DOI: 10.1111/jmp.12381
  • ISSN: 0047-2565; 1600-0684
  • Schlagwörter: General Veterinary ; Animal Science and Zoology
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  • Beschreibung: <jats:title>Abstract</jats:title><jats:p>Cervicovaginal bacteria cause inflammation which in turn increases <jats:styled-content style="fixed-case">HIV</jats:styled-content> risk. Profiling the cervicovaginal microbiome, therefore, is instrumental for vaccine development. We show that the microbiome profile captured by cervicovaginal lavage is comparable to samples obtained by vaginal swabs. Thus, lavage may serve as a sampling strategy in <jats:styled-content style="fixed-case">NHP</jats:styled-content> vaccine studies.</jats:p>