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Medientyp:
E-Artikel
Titel:
Mobile genetic elements: in silico, in vitro, in vivo
Beteiligte:
Arkhipova, Irina R.;
Rice, Phoebe A.
Erschienen:
Wiley, 2016
Erschienen in:
Molecular Ecology, 25 (2016) 5, Seite 1027-1031
Sprache:
Englisch
DOI:
10.1111/mec.13543
ISSN:
0962-1083;
1365-294X
Entstehung:
Anmerkungen:
Beschreibung:
Mobile genetic elements (MGEs), also called transposable elements (TEs), represent universal components of most genomes and are intimately involved in nearly all aspects of genome organization, function and evolution. However, there is currently a gap between the fast pace of TE discovery in silico, driven by the exponential growth of comparative genomic studies, and a limited number of experimental models amenable to more traditional in vitro and in vivo studies of structural, mechanistic and regulatory properties of diverse MGEs. Experimental and computational scientists came together to bridge this gap at a recent conference, ‘Mobile Genetic Elements: in silico, in vitro, in vivo’, held at the Marine Biological Laboratory (MBL) in Woods Hole, MA, USA.