Beschreibung:
<jats:title>Abstract</jats:title><jats:sec><jats:label /><jats:p><jats:styled-content style="fixed-case">RV</jats:styled-content> systolic function is important early after <jats:styled-content style="fixed-case">HT</jats:styled-content>; however, it has not been critically assessed in children using quantitative measures. The aim of this study was to describe the most validated and commonly used quantitative echocardiographic measures of <jats:styled-content style="fixed-case">RV</jats:styled-content> systolic function early after pediatric <jats:styled-content style="fixed-case">HT</jats:styled-content> and to assess associations with qualitative function evaluation and clinical factors. <jats:styled-content style="fixed-case">RV</jats:styled-content> systolic function was quantified on the first post‐<jats:styled-content style="fixed-case">HT</jats:styled-content> echocardiogram >24 hours after cardiopulmonary bypass using two‐dimensional <jats:styled-content style="fixed-case">TAPSE</jats:styled-content>, Tricuspid annular S’, <jats:styled-content style="fixed-case">FAC</jats:styled-content>, and <jats:styled-content style="fixed-case">MPI</jats:styled-content>. In 145 patients (median age 7.6 years), quantitative <jats:styled-content style="fixed-case">RV</jats:styled-content> systolic function was markedly abnormal: mean <jats:styled-content style="fixed-case">TAPSE </jats:styled-content><jats:italic>z</jats:italic>‐score −8.43 ± 1.89; S’ <jats:italic>z</jats:italic>‐score −4.36 ± 1.22; <jats:styled-content style="fixed-case">FAC</jats:styled-content> 24.4 ± 8.34%; and <jats:styled-content style="fixed-case">MPI</jats:styled-content> 0.86 ± 0.51. Few patients had normal quantitative function: <jats:styled-content style="fixed-case">TAPSE</jats:styled-content> (0%), S’ (1.2%), <jats:styled-content style="fixed-case">FAC</jats:styled-content> (9.4%), and <jats:styled-content style="fixed-case">MPI</jats:styled-content> (28.4%). In contrast, 48.3% were observed as normal by qualitative assessment. Most clinical factors, including diagnosis, pulmonary vascular resistance, posttransplant hemodynamics, inotropic support, and rejection, were not associated with <jats:styled-content style="fixed-case">RV</jats:styled-content> function. In this large pediatric <jats:styled-content style="fixed-case">HT</jats:styled-content> population, <jats:styled-content style="fixed-case">TAPSE</jats:styled-content>, S’, <jats:styled-content style="fixed-case">FAC</jats:styled-content>, and <jats:styled-content style="fixed-case">MPI</jats:styled-content> were strikingly abnormal early post‐<jats:styled-content style="fixed-case">HT</jats:styled-content> despite reassuring qualitative assessment and no significant association with clinical factors. This suggests that the accepted normal values of these quantitative measures may not apply in the early post‐<jats:styled-content style="fixed-case">HT</jats:styled-content> period to accurately grade <jats:styled-content style="fixed-case">RV</jats:styled-content> systolic function, and there may be utility in adapting a concept of normal reference values after pediatric <jats:styled-content style="fixed-case">HT</jats:styled-content>.</jats:p></jats:sec>