Beschreibung:
<jats:p>1. The ability of the three nitrophenols, <jats:italic>m</jats:italic>‐nitrophenol, <jats:italic>p</jats:italic>‐nitrophenol and 2,4‐dinitrophenol, to inhibit acid secretion and stimulate oxygen uptake by gastric mucosa paralleled their extent of dissociation at physiological pH.</jats:p><jats:p>2. Oligomycin inhibited oxygen uptake by gastric mucosa, and showed a tendency to inhibit acid secretion.</jats:p><jats:p>3. 2,4‐dinitrophenol lowered the value of the ratio between acid secretion and the associated oxygen uptake. Oligomycin did not affect the value of this ratio.</jats:p><jats:p>4. It would appear that a non‐phosphorylated high‐energy intermediate of oxidative phosphorylation might be involved in acid secretion by gastric mucosa.</jats:p>