• Medientyp: E-Artikel
  • Titel: Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2
  • Beteiligte: Ler, Lian Dee; Ghosh, Sujoy; Chai, Xiaoran; Thike, Aye Aye; Heng, Hong Lee; Siew, Ee Yan; Dey, Sucharita; Koh, Liang Kai; Lim, Jing Quan; Lim, Weng Khong; Myint, Swe Swe; Loh, Jia Liang; Ong, Pauline; Sam, Xin Xiu; Huang, Dachuan; Lim, Tony; Tan, Puay Hoon; Nagarajan, Sanjanaa; Cheng, Christopher Wai Sam; Ho, Henry; Ng, Lay Guat; Yuen, John; Lin, Po-Hung; Chuang, Cheng-Keng; [...]
  • Erschienen: American Association for the Advancement of Science (AAAS), 2017
  • Erschienen in: Science Translational Medicine
  • Sprache: Englisch
  • DOI: 10.1126/scitranslmed.aai8312
  • ISSN: 1946-6234; 1946-6242
  • Schlagwörter: General Medicine
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:p>Bladder cancer with loss of KDM6A expression is vulnerable to inhibition of EZH2.</jats:p>