• Medientyp: E-Artikel
  • Titel: Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas
  • Beteiligte: Panwalkar, Pooja; Tamrazi, Benita; Dang, Derek; Chung, Chan; Sweha, Stefan; Natarajan, Siva Kumar; Pun, Matthew; Bayliss, Jill; Ogrodzinski, Martin P.; Pratt, Drew; Mullan, Brendan; Hawes, Debra; Yang, Fusheng; Lu, Chao; Sabari, Benjamin R.; Achreja, Abhinav; Heon, Jin; Animasahun, Olamide; Cieslik, Marcin; Dunham, Christopher; Yip, Stephen; Hukin, Juliette; Phillips, Joanna J.; Bornhorst, Miriam; [...]
  • Erschienen: American Association for the Advancement of Science (AAAS), 2021
  • Erschienen in: Science Translational Medicine, 13 (2021) 614
  • Sprache: Englisch
  • DOI: 10.1126/scitranslmed.abc0497
  • ISSN: 1946-6234; 1946-6242
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  • Beschreibung: Childhood posterior fossa group A ependymomas demonstrate integrated metabolic and epigenetic pathways that can be disrupted by metformin.