• Medientyp: E-Artikel
  • Titel: Gene Transfer to Myxobacterium by Escherichia coli Phage P1
  • Beteiligte: Kaiser, Dale; Dworkin, Martin
  • Erschienen: American Association for the Advancement of Science (AAAS), 1975
  • Erschienen in: Science
  • Sprache: Englisch
  • DOI: 10.1126/science.803710
  • ISSN: 0036-8075; 1095-9203
  • Schlagwörter: Multidisciplinary
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:p> <jats:italic>Myxococcus xanthus</jats:italic> is a bacterium with an interest for studies of development because it has an organized multicellular phase in its life cycle. Bacteriophage P1 can adsorb to <jats:italic>M. xanthus</jats:italic> and inject its DNA into this organism despite the wide taxonomic gap separating myxococcus from <jats:italic>Escherichia coli</jats:italic> , the source of P1. A specialized transducing derivative of P1, called P1CM, can carry a gene for chloramphenicol resistance from <jats:italic>E. coli</jats:italic> into <jats:italic>M. xanthus</jats:italic> and generate unstable drug-resistant strains. </jats:p>