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Medientyp:
E-Artikel
Titel:
Nanoscale-length control of the flagellar driveshaft requires hitting the tethered outer membrane
Beteiligte:
Cohen, Eli J.;
Ferreira, Josie L.;
Ladinsky, Mark S.;
Beeby, Morgan;
Hughes, Kelly T.
Erschienen:
American Association for the Advancement of Science (AAAS), 2017
Erschienen in:
Science, 356 (2017) 6334, Seite 197-200
Sprache:
Englisch
DOI:
10.1126/science.aam6512
ISSN:
0036-8075;
1095-9203
Entstehung:
Anmerkungen:
Beschreibung:
<jats:title>How the flagellum knows when to stop</jats:title>
<jats:p>
The bacterial flagellum is important in bacterial pathogenesis and biofilm formation. It is a rotary nanomotor that allows bacteria to propel themselves through liquids and across surfaces. Researchers interested in nanoscale robotics use the bacterial flagellum as a model for a machine that self-assembles on the nanoscale. Cohen
<jats:italic>et al.</jats:italic>
examined exactly how the flagellum precisely measures its shaft so that it spans, but does not extend beyond the edge of, the periplasm. The growing flagellum uses a mechanism by which it “senses” when it hits the outer membrane and stops growing. Changing the width of the periplasmic space by remodeling a particular lipid changed the length of the flagellar shaft.
</jats:p>
<jats:p>
<jats:italic>Science</jats:italic>
, this issue p.
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</jats:p>